Which TCA has a dosing range of 15-60 mg/day?

The correct choice for a TCA with a dosing range of 15-60 mg/day is Protriptyline. This tricyclic antidepressant is known for its specific dosing guidelines that fit within this range. Protriptyline is typically used to treat depression, particularly in patients who have also experienced sleep disturbances. Its dosing is carefully managed to optimize its effectiveness while minimizing potential side effects, which are common with this class of medications.

In contrast, other TCAs have different dosing guidelines. For example, Doxepin is usually administered within a broader range, often starting at higher doses, especially in its formulation for treating anxiety or insomnia. Imipramine has a higher starting and maximum dosing range primarily due to its usage in a wider variety of mental health conditions, including severe depression and some anxiety disorders. Amoxapine is also dosed differently, typically starting at a higher dose and having adjustments that exceed 60 mg/day in some cases.

Understanding the specific dosing recommendations for each TCA helps guide treatment decisions and ensures that patients receive the optimal dose for their condition.