What is the only indication for Milnacipran?

Milnacipran is primarily indicated for the treatment of fibromyalgia. It is a serotonin-norepinephrine reuptake inhibitor (SNRI) that has been shown to be effective in alleviating the pain and improving function in individuals suffering from this condition. Fibromyalgia is characterized by widespread pain, often accompanied by fatigue, sleep disturbances, and cognitive issues, making effective pain management crucial for those affected.

While Milnacipran has an impact on mood and pain perception due to its pharmacological properties, its specific approval and indication for use are centered on managing fibromyalgia. The other options, such as chronic low back pain, generalized anxiety disorder, and depression, are conditions for which other medications might be indicated, but they are not the primary or approved uses for Milnacipran. Therefore, the focused efficacy of Milnacipran in fibromyalgia justifies its designation as the correct response to the question regarding its sole indication.