Besides increased appetite, which other side effect is associated with Mirtazepine?

Mirtazapine is an antidepressant that is commonly associated with certain side effects as it interacts with various neurotransmitter systems in the brain. Somnolence, or increased sleepiness, is a well-known side effect of mirtazapine due to its antagonistic effects on histamine receptors. This sedative effect can be particularly beneficial for patients who experience insomnia or anxiety along with depression.

The mechanism of mirtazapine involves the enhancement of norepinephrine and serotonin transmission while simultaneously blocking certain receptors that can lead to side effects such as sleep disturbances. Therefore, for many patients, the somnolence can be a desired effect, especially if they struggle with sleep issues.

In contrast, the other options might not be as strongly linked to mirtazapine's pharmacological profile. While decreased libido and increased anxiety can occur with some antidepressants, they are not widely reported as common side effects specific to mirtazapine. Hyperactivity is not typically associated with mirtazapine's sedative properties and overall calming effects. Thus, somnolence stands out as a significant side effect linked to the drug.